The World Cup will now have to go on without the two biggest stars in the global game.
Ronaldo and Messi have won the biggest individual prize eight times between themselves.
France edged Messi’s Argentina 4-3 with Luis Suarez’s Uruguay defeating Cristiano Ronaldo’s Portugal out of the FIFA World Cup via 2-1 score.
Uruguay and France have qualified to the quarterfinals.
Champions Germany were eliminated in the Group stages with all African teams also failing to proceed beyond the first round.